How much Bacon gives you Liver Failure? What about Colon Cancer?

How much Bacon gives you Liver Failure? What about Colon Cancer?

In February 1977, a 42 year old woman was
admitted to the hospital with deep jaundice, shivers and hemolytic anemia – a type of anemia
where her red blood cells were being destroyed faster than her body could make them. She went on to develop a “hepatic precomatose
condition,” – a type of impairment of consciousness you see in severe liver disease. The doctors found she had a shrunken liver
and an enlarged spleen. With multiple red blood cell transfusions,
the woman recovered, but the cause of this mysterious liver disease eluded doctors for
quite a while. One day, her husband suddenly brought over
some cooked blackberries. This was a bit odd since he rarely visited
her and in fact, hospital staff advised her not to accept any outside food. They decided to feed the blackberries to some
mice. …and The mice died. They sent the blackberries off for analysis
and found that they contained about 300milligrams of the nitrosamine N-Nitrosodimethylamine,
NDMA. The woman’s recovery was only temporary. After discovering the details of her assassination,
her mental and physical state progressively worsened over the following months. The husband was convicted but unfortunately
the woman died. So what does this have to do with bacon? Well, Nitrosamines are the cancerous compounds
suspected to form from the nitrate and nitrites found in processed meat. But the dose the woman was given was 300 milligrams
– just how big is that? We’ll get to that in a moment. “The alarming warning from the World Health
Organization’s cancer research arm that goes like this: processed meat causes cancer and
red meat probably does too.” In 2015, the IARC declared that processed
meat is a carcinogen, a cancer causing agent. Suspect harmful compounds in processed meat,
and analysis of more than 800 observational studies is what led them to their conclusion. Billowing Backpacks radioactive man, that’s
a lot of studies! However, in the report, all the 127 studies
on colorectal cancer, as shown in table 2.2, used questionnaires as the data collection
method. Actually this type of study, an observational
study, is very very common in nutrition research. The questionnaires usually have a similar
format – Here’s one from Cambridge University. Do you happen to know what your average use
of bacon was for all of last year? Then, what these questionnaires have difficulty
taking into account is: Do you eat your bacon like this or like this? Or like this? Back in 1994, a study “found” that hot
dogs increase brain cancer risk in children. “They asked the people: did you eat a hot
dog? They didn’t ask them: Did you put it in a
bun, did you put ketchup on it? That’s important because it may be that it’s
not the hot dog at all that’s causing this increase risk of cancer, maybe it’s the bun,
maybe it’s the ketchup, maybe it’s the mustard so…” I thought this newscaster had a decent point
– think about the type of people who eat the most hot dogs – what other foods are they
likely to eat more of? For the record, I’m not here to say processed
meat is some great health choice. I’d say if you’re going to eat meat, then
make it good quality fresh meat. But, let’s be realistic: is a breakfast
of an egg, avocado, and some bacon really that bad for you? The main suspect bad compounds put specifically
in processed meat are nitrates and nitrites. During heat processing of the meat, a small
portion of the additive sodium nitrite is suspected to turn into the cancerous nitrosamines
like the earlier mentioned NDMA. But, the acidic nature of our stomach is suspected
to allow nitrates and nitrites to turn into nitrosamines in the body during digestion. Now, there are some major issues with the
nitrate nitrite idea. First, both compounds are found in vegetables. This study found that in italians vegetables
provided 5.5 times the nitrate and nitrite of cured meat. In fact celery juice which has very high concentrations
of nitrate, and is used to make the all natural “no added nitrates or nitrites” processed
meat. In fact, there is a cycle in the body where
nitrate is turned into nitrite and nitrite is turned into nitric oxide then nitric oxide
is turned back into nitrate. Part of this cycle takes place in the mouth,
so there is naturally plenty of nitrite in our saliva. “…what the hell, you drooled on me!” OK So in the body, nitrite is reduced to nitric
oxide… and Nitric oxide is regarded as essential for health because your body uses this molecule
to relax blood vessels. This paper refers to both nitrate and nitrite
as nitric oxide therapeutics. As the paper explains, nitrate and nitrite
have been shown to be good for blood pressure, mitochondrial efficiency, exercise performance,
and have a therapeutic effect on pulmonary hypertension.[R] Which is why, you’ll find nitrate supplements
like these beet root powder ones designed to improve blood flow and heart health, reduce
blood pressure and improve exercise performance. Now hold on a minute, because the point is
not that you should be scared of bacon and celery sticks and beet powder . A Chemist
and Biochemist who has published relevant research in several journals like the American
Journal of Physiology, Dr. Mark Miller, says that nitrate and nitrite are not nitrosating
species – that is, these molecules cannot directly form cancer causing nitrosamines,
so whether your bacon contains inorganic sodium nitrite or all natural nitrate from celery
juice, it’s not getting turned into the cancerous nitrosamines in your body. I won’t get into the details here, but in
the description I’ll link to an article where he clearly lays out the chemistry and
biochemistry for this. Moving on, here’s a study where researchers
wanted to see how processed meat affected the development of colon cancer. They first injected the rats with azoxymethane,
a compound known to cause colon cancer. Surprisingly, they found that not only did
a bacon diet not cause cancer, it actually consistently protected them from the cancer-
bacon reduced the number of precancerous lesions in rats injected with the azoxymethane. But of course this is just one study, so let’s
move on. What about cancerous Nitrosamines already
present in bacon, frankfurters or salami thanks to heat processing. Nitrosamines are definitely bad for you, that’s
not in question – in high enough doses they mess up your liver, and yes, can cause cancer. But precisely how much can a human tolerate
without having any issues? After all, few people would suspect a half
glass of wine a couple days a week to be bad for you. “Many studies have shown that drinking a moderate
amount of red wine can help the fight against heart disease, alzheimer’s and some cancers.” But, 50 half glasses of wine in one night
could cause serious injury to your liver. The dose is important. So, we need to use some logic to get an idea
of how much nitrosamine a person can tolerate: This is a table from the IARC report looking
at nitrosamines in processed food. The LD-50 is a measure of toxicity looking
at what dose will kill half of the people given that dose. Based on the LD50 data, the nitrosamine NDMA
appears to be the most toxic. NDMA – this is the same compound given to
the woman mentioned at the start of the video. 300 milligrams of NDMA is the amount she was
given in the blackberries – how much processed meat do you have to eat to get that amount? Based on the highest value provided in the
table from the IARC, 84 micrograms per kilogram of Frankfurters, you would need to eat 3500
kilograms of frankfurters. “Thousands of pounds of wieners are produced
daily…” That is more than the weight of a Hummer H2
of frankfurters to get the same dose as the woman who died from the blackberries. OK But we don’t want to know how much to
eat to die, we want to know how to not get cancer. This study put various doses of NDMA in the
drinking water of over 4000 rats and followed them over their lifespan, about 2 years. They found that “since the experiment continued
on into extreme old age, effects became measurable at doses of only 0.01 to 0.02 mg/kg/day,”
that is, they only got the cancerous tumors at .01 mg/kg per day and higher. Using Anroop Nair’s human equivalent dose
conversion, we can estimate that a 70kg human would need a dose of .0013milligrams or 1.3
micrograms per kilogram of NDMA. So, assuming we can apply this mouse data
to humans, you would have to eat more than 1.1 kilograms, which is 2 and a half pounds
or 2700 calories of frankfurters a day, for years, to develop a cancerous tumor at some
point probably in the second half of your life. That’s 80 times the amount of Nitrosamine
the average American actually consumes. To give you some perspective, the LD50 of
Oxalate is 25 grams, boiled spinach is about 0.60% oxalate, meaning 4.3kg of boiled spinach,
eaten once, has a 50% chance to kill you. I’m not trying to say Nitrosamines are harmless,The
point is, if we’re going to point at a substance in some food as a mechanism for that food
being bad, we need to be realistic with the dose – what is an actually realistic amount
of that substance a person can get from food? There are many other ideas for why processed
meat is bad for us that I didn’t explore, but most of these can be applied to red meat
in general, so stick around because we’ll take a look at those in my next video. One more thing, the IARC report concluded
that “Each 50 gram portion of processed meat eaten daily increases the risk of colorectal
cancer by 18%.” That doesn’t mean people who eat processed
meat raise their absolute risk of colon cancer from zero to an 18% chance. What that really means is, for example for
100 Australians not eating processed meat, over their lifetime, 8 will get colorectal
cancer. For 100 Australians eating 3 slices of bacon
a day, 9 will get colorectal cancer. The other thing about this report is, if you’re
familiar with epidemiology you’d know that a study with a relative risk under 2 is probably
noise and should be thrown out. More than 2/3rds of the studies on colorectal
cancer did not find a relative risk over 2. Another thing is that these studies don’t
differentiate between organic prosciutto that is just pork and salt and cheddar cheese stuffed
hot dogs with added corn syrup and soybean oil. and once again For the record, I’m not saying
we should all eat more processed meat. Actually I rarely choose to eat processed
meat and I think meat quality needs to be prioritized much more by those who can afford
it. I just wish points for or against foods were
more realistic. “This program was made possible by the generous
donations from my Patreon patrons and, viewers like you.”

100 Replies to “How much Bacon gives you Liver Failure? What about Colon Cancer?”

  1. Many of you asked about another video saying this video is wrong.
    ◼︎(Full response here: ) Flaws with that video at a glance:
    -While I did not mean to suggest “sodium nitrite added to bacon makes it good for the arteries” in my video, he does not present sufficient evidence to claim nitrate/nitrite from the plants is good whereas nitrite from bacon is bad. (Fun fact: 93% of the total ingestion of nitrite is derived from saliva)
    -Skips over some very complicated science presented by a Pharmacology & Physiology PhD with ad hominem logic.
    -Misinterprets me as saying ‘nitrosamines cannot be formed in the body,’ I didn’t say this.
    -Confuses red meat with processed meat.
    -Uses studies that are looking at “apparent total nitrosamines” rather than specific nitrosamines in meat. This is important because there are several types of nitrosamines with different severity of effects on the body.
    -His data for endogenous formation of NDMA is based on ​in vitro​ studies ​looking not at red meat,​ but fish, and in specific, a type of fish that has the specific precursor to NDMA (DMA) in its muscle. Meat does not typically have this precursor. The study even found no NDMA formation from grilled meat.
    -He confuses ​"total endogenously formed NDMA"​ with ​"NDMA formed endogenously as the result of eating red meat/processed meat."​ (The study he references makes no mention of endogenous NDMA formation ​via meat consumption​.)

  2. This guy doesn't understand what is a Relative Risk, has not taken a single class in biology much less chemistry. Cero validity for this video.

  3. Unrelated, but could you do a video on tooth decay as a result of diets? Ancient humans didn’t have hardly any tooth decay, but as soon as agriculture rolled around, it changed.

  4. Damn, the lies and misinformation in this video. I should be shocked, but these videos are so common that I'm really not that surprised.

  5. Experts have concluded that you should all eat a strictly plant based (aka: slave) diet and bugs. Also just shut up, sit down and watch your regularly scheduled programming, we'll tell you what to do; we'll tell you if, when and what to think.

  6. A small amount like everyday or so over 20 or 40 years piles up. That is the cause. To much shit in processed food. Eat plant based and organic so you at least minimize your risk. You only get one shot at life.

  7. Whoa, I didn't knew the study on "red meat increases risk of cancer" was that badly flawed. Makes me think whoever conducted it already had a result in mind before even starting.

  8. Thanks for the great video. If you look at the actual studies and available data you can reach much the same conclusions about second hand smoke i.e. it is harmless. There is so much bad science out there, especially regarding food and nutrition. Another example is MSG. Another harmless additive that is in lots of processed food. Or wheat gluten. Let the flaming commence.

  9. When given nutritional advice you should always ask: "Who profits most? " if everyone follows this advice. More often than not it's the food industry or some religious group or other… Small farmers certainly don't. #supportsmallfarmers #eatlocalgrown

  10. So don’t eat candy, don’t eat snacks, keep processed food on the minimum and don’t get fat. Voila you have become healthy

  11. You know there is nitrate/nitrite free bacon. Also uncured, antibiotic & sugar free, which is what I eat (sparingly.) Dont let the “perfect” be the enemy of the “good.” Enjoy your life, don’t be a dick.

  12. So, just enjoy you bacon. For thousands of years nitrates were used by all ancient cultures to preserve their food, so no worries. As everything in life, too little won't do you nothing, too much will probably kill you………..Good video.

  13. I appreciate the work that went into this video, but I really wish there was some very conclusive guidance regarding such things as processed meat. Maybe in a few years. Until then, I'll try to limit my red meat intake and choose organic, and keep doing Intermittent Fasting which cleans up the cells, i.e., good for cancer prevention.

  14. How much sugar will give you cancer? Guarantee a shitload more than bacon would!! Guarantee this fat twat consumed tons of soda!!

  15. Veganism causes mental illness. I was one for 8 years, and I was led astray by the deluded cult that vegans are. Humans need meat. Everything in moderation.

  16. I think the UN warning was mostly some sort of lesser of two evils thingy.
    For example, sure, cured meat only raises the chances of getting cancer slightly, but that slightly in 8 billion is millions of lives saved.

  17. As a scientist, I've had a profound revelation that all food ~leads to death.
    To reiterate, as shown in millions of studies, if you eat, you WILL! die. So don't.

  18. why in that study, bacon prevented colon cancer, absence of sugar in the diet. Sugar is the culprit, but food corporation who profit out of high sugar processed food will not fund research against their business.

  19. Your explanation is on point and very accurate. I hope you do a video about soy milk, whether it's actually good or bad. Because there are conflicting claims on the internet about it.

  20. It's all BS fear mongering. The Us Government set up the my plate (the food pyramid) to sell corn, grains,and sugar. In this they make big money. If it were for public health we would not be such an unhealthy nation dying of heart disease, diabetes, fatty livers. Red meat does not cause cancer, pink salts don't cause cancer. Just look who broke the story someone who sold there sole for fame. the person that made this if fear mongering.

  21. A 70kg human would not stay 70kg for very long if they were eating 2700 calories. Even if they were very active, they would creep towards 100kg, so that amount would go up. You'd almost have to have an exclusively processed meats diet and probably weigh 125+kg to come close to hitting that risk category.

  22. Absolutely beautiful work. Thank you for reading through the research papers, and delivering proper assessment of same. Most media people are too dimwitted to do so.

  23. The federal government is worred about NITRATES, and their Spraying the Hell out of our Sky's with Chemtrails with billions gallons of toxic chemicals which goes air born and falls to the ground that's making humans Sick all over the World"
    Ps I'll give up Nathan hot dogs, if they stop Chemtrailing our SKY'S"

  24. I think I'm mostly concerned about the total number of Australians without legs. Seriously, who knew it was 100%? 😂

  25. WTF is this shyt more leftists vegan Crypto-communism propaganda there is nothing wrong bacon cowboy‘s been eating it since time began you never heard of them complaining

  26. Nitrates and nitrites do not cause cancer and they can show you no studies to prove it. Plants contain far more nitrates and nitrites than any meats.

  27. Could you make a video looking at smoking? There’s a lot of science behind it all which I don’t really trust. Thanks.

  28. When I see Lester on the screen, I automatically say, "lie to me Lester"!
    Junk science works like this. People who stand on street corners take more busses than the general population. Any questions?
    It's statistics. A wise man once said, there are lies, damn lies, and statistics!
    This presentation creates more questions than it answers. Was the intent to inform or fearmonger like Lester does every day? IDK.

  29. So, what I'm hearing is bacon is good, very good. And a litre of wine a day is perfectly fine.

    To be real for a second, the last few seconds of your vid is the real problem; I'm so high, what was I going to say… oh yes, the problem is… f**k. Perception!!! The problem is in how the studies, through media, etc. are presented to us.
    Therefore, the problem is us blindly trusting. Sad, that we can't trust each other.
    Sad that 'hype' is king.
    Stoopid neurochemicals. psh

  30. In Islam. Pork and alcohol is forbidden. You are to sleep in your left or right side, never on your stomach. Fasting is good for you. Specially day on and day off fasting.

  31. What Ive Learned = cia disinfo operation using reverse psychology. (I dont eat much meat myself (im on your side, NOT) but Dont believe bacon causes cancer)

  32. Can’t wait for government food rationing, coming to a USA real soon ! Get ready fat and lazy food stamp loving illegals, no more bacon , dear

  33. Omg this May one the dumbest videos on the internet smfh thank god we have intelligent people like Mic The Vegan to set this shit straight

  34. can we go backward in the food department… obesity is industry fault. no healthy food anymore everything is processed.

  35. This is like going to Fox and friends for your news. These talking points come from the industry hurt by the “real science”. Did you get a check, or did you do it for free?

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